How to Deal with Depression & Anxiety: List of Top 10 Best Natural Antidepressants

Although everyone can experience sadness from time to time, not everyone will suffer from depression. Chances are that you don’t have a good understanding of what living with this mental illness is like if you’ve never been depressed.

Depression is like a big black dog that feeds on your fear and anxiety. The more you’re depressed, sad, and anxious, the larger the dog grows — until it eats you alive.

The illness affects both our mood and our ability to feel, think, and function. It dampens feelings of pleasure, makes a person less able to bond with other people, limits creativity, and washes away hope in the worst scenario.

Depression is also often accompanied by deep emotional pain, experienced by the person suffering from it, but also its close family and friends.

While you may think that depression is just an excuse for somebody’s laziness or a lack of will for change, it just shows how much depression is misunderstood.

When you’re depressed, you genuinely believe that change isn’t possible for you; that the overwhelming darkness will stick with you forever.

In this article, we leave no stone unturned when it comes to coping with depression. We’ll elaborate on the symptoms, diagnosis, treatments, and natural remedies.

How to Cope with Depression: Frequently Asked Questions & Answers

Looking for ways to cope with depression? Here we’ve prepared some common questions and answers — from diagnosis to available treatments.

How do I know if I’m depressed?

Common signs of depression in adults include feelings of irritation, inability to focus, sadness, emptiness, anxiety, frustration, anger, and feelings of guilt. Individuals with depression may also experience fluctuation of appetite and loss of interest in previously enjoyed activities.

What causes depression?

Trauma, such as the loss of someone close, as well as changes in life circumstances, relationship problems, and genetics, can all contribute to the development of depression. People who abuse alcohol and drugs are more likely to suffer from depression. The illness can occur spontaneously or run in families.

Is depression a lifelong condition?

Depression doesn’t have to be a lifelong condition. It can be successfully treated with behavioral therapy and available treatments that help reduce symptoms and improve the overall quality of life. That being said, depression can recur, sometimes caused by the same factors that spurred its development in the first place. If a patient feels better, they may want to discontinue the treatment, which can result in a relapse.

How long does it take for antidepressants to work?

Anywhere between two and eight weeks for antidepressants known as SSRIs (e.g., Prozac).

Is alcohol a depressant?

Yes, alcohol can compromise your cognitive performance, cause memory problems, and increase anxiety — although many people drink it to relax and relieve stress.

How Many People Suffer from Depression?

According to statistics, 17.3 million, or 7% of American adults in the United States experienced at least one major depressive disorder in the past year, as reported by the National Institute of Mental Health.

Conclusion?

Depression is one of the most common mental illnesses in the United States (1).

Furthermore, according to a 2021 State of Mental Health in America report, conducted by a non-profit organization, Mental Health America, an additional 460,000 people (0.15%) had suicidal thoughts between the 2016-2017 calendar year and the 2017-2018 calendar year (2).

On a positive note, there are many effective treatment options for depression. If you’re looking for a way to cope with your illness, you’ll need to take a holistic approach, as there’s no magical pill that would cure it right away.

Raising awareness about the need to treat depression is paramount, considering that roughly two-thirds of patients with depression didn’t receive the care they need — that’s the data from the journal Neuropsychiatric Disease and Treatment (3).

How to Cope with Depression: Identifying the Symptoms

If sadness isn’t the independent cause of depression, then what is? How to tell the difference between a bad period and depression?

According to the American Psychiatric Association’s updated Diagnostic and Statistical Manual of Mental Disorders (DSM-5), which is a manual for psychiatrists to diagnose mental conditions, the diagnosis of major depressive disorder is based on careful observation of a patient for at least two weeks.

If a person has experienced at least five of the following symptoms most of the day, nearly every day, for the said period, they may receive a diagnosis of clinical depression (4):

  • Feelings of being empty and worthless
  • Loss of interest in activities and people that you once enjoyed
  • Dramatic fluctuation in your appetite or weight not related to eating habits
  • Frequent fatigue
  • Difficulty concentrating and making decisions
  • Recurring anxiety
  • Insomnia
  • Recurrent suicidal thoughts

One of the major symptoms that is used to diagnose MDD is a constant low mood or a loss of interest or pleasure.

The symptoms must also not be caused by substance abuse or an underlying medical condition, such as nutritional deficiencies, thyroid disorders, or brain tumors.

Of course, if these symptoms appear temporarily, you may not have depression at all. However, when they make it difficult to function normally, it’s an indicator that you may be developing a major depressive disorder.

The best way to start coping with depression is to consult your doctor, a psychiatrist, or a psychotherapist. If you don’t feel like visiting a clinic to receive a diagnosis, Google up “clinical depression,” and you’ll find links to a clinically approved depression test known as the PHQ-9 patient health questionnaire.

The test is short and easy to take – you can immediately notice if your score suggests you may have depression.

Please note

If you suspect you have depression, or if your symptoms are severe and you’re having suicidal thoughts, call the National Suicide Prevention Lifeline at 800-723-8255 or the National Substance Abuse and Mental Health Services Administration Helpline at 800-662-4357. Both are available 24/7, 365 days a year, and free of charge.

Different Types of Depression

Persistent depressive disorder (PDD)

Also known as dysthymia, PDD is diagnosed in individuals who experience at least two of the symptoms of major depression for a minimum of two years at a time. The symptoms range from less severe to severe and can manifest both as PDD and MDD at the same time, transforming into a condition known as double depression (5). People with PDD are often taken as sullen, pessimistic, fussy, and cranky rather than being recognized as having a treatable condition.

Bipolar disorder

This type of depression was formerly called manic depressive disease. It is characterized by mood swings that range from extreme highs (mania) and episodes of low mood (depression), broken by periods of normal mood in the meantime (6). An estimated 2.8% of U.S. adults, or more than 6 million people, suffer from bipolar disorder (7).

Seasonal affective disorder (SAD)

People with this type of depression usually suffer from it at the beginning of the fall and throughout the winter. SAD is often linked to changes in sunlight and causes sleepiness, weight gain, and cravings for high-carb foods (8).

Premenstrual dysphoric disorder (PMDD)

This is a more severe form of premenstrual syndrome (PMS). PMDD usually starts a week or two before a woman’s period and stops two or three days after menstruation starts (9).

Perinatal (or postpartum) depression (PDD)

This condition is diagnosed in mothers who had a major depressive disorder shortly after giving birth (10). PDD is usually caused by a combination of factors, such as a sharp fluctuation in hormone levels following childbirth. Feelings of deep anxiety, sadness, or exhaustion are much intense and last longer than a typical low mood.

How to Tell If You Have Depression

One reason depression can be difficult to diagnose is that the symptoms can vary widely between individuals and sometimes can be accompanied by atypical symptoms.

For example, people with depression may show it by acting aggressively, resentfully, or irritable. These behaviors can be indicative of “hidden” depression, as stated by a 2017 report in Psychiatric Times (11).

This may seem surprising at first, but when you consider several other contributors, such as alcohol or drug abuse, or childhood trauma, you can see the bigger picture.

Individuals with anxiety disorders are at a higher risk for developing depression — it also works the other way round. According to the National Alliance on Mental Illness, around 60% of people who have anxiety will also experience symptoms of depression; the same applies to people with depression demonstrating symptoms of anxiety (12).

Experts link the above phenomenon to a genetic predisposition (13).

If you have depression, you may also show psychosomatic symptoms, meaning that instead of showing itself as a mood disorder, the prevalent symptoms may be very general things like aches, dizziness, headaches, back pain, or digestive issues (14).

As you can see, it’s often difficult to figure out whether depression is causing the physical symptoms, or if it’s the opposite.

Causes of Depression

It’s not yet understood why some people develop depression and others don’t. The illness can occur spontaneously, without any specific triggers. It’s also backed by science that once you’ve experienced one depressive disorder, you have a higher risk of having another later in life.

In a study published by Psychological Medicine, the authors found that more than 13% of people who recover from their first episode of clinical depression experience another episode within 5 years. 23% have it within 10 years, and 42% within 20 years (15).

To cope with depression, it’s worth taking another look at this condition. Psychiatrists today consider depression a “bio-psycho-social” illness that is most likely caused by overlapping psychological, physiological, and social factors (16).

Here are some of the most common risk factors for depression:

Genetics

Many studies have associated depression with genetic predispositions, including the one involving over 2 million people, and published in the 2019 edition of the journal Neuroscience. The study linked 269 genes to depression (17). However, genes alone aren’t believed to be solely responsible for depression; there are also other risk factors at play.

Neurotransmitters

Depression can stem from low levels of certain neurotransmitters, although scientists tend to stray from this concept nowadays. The current theory is that depression can be caused by impaired nerve cell connections in the brain, nerve cell growth, or abnormal functioning of nerve circuits (18).

Inflammation

Numerous studies suggest that stress-related or disease-related inflammation is the cause of chemical changes in the brain that can cause or deteriorate depression in certain individuals. It can also affect the way a person responds to pharmacological treatment (19).

Life struggles

The World Health Organization (WHO) reports that psychological and social factors, such as low socioeconomic status, stressful life, loneliness, or a history of abuse, can play a determining role in the development of depression (20). Adults with clinical depression have a higher rate of childhood trauma compared with people who haven’t experienced abuse, according to a 2016 study published in the journal Translational Psychiatry (21).

Traumatic Brain Injury (TBI)

Another common type of depression is a traumatic brain injury. Approximately 3 million people each year seek aid in emergency rooms for TBIs (better known as concussions), following a fall, assault, car accident, blow to the head, bump, and sports- and workplace-related injuries, as reported by the Centers for Disease Control and Prevention (22). Over 50% of those patients meet the criteria for major depression three months following their injury (23).

How Do Men and Women Cope with Depression

There’s a large gender gap when it comes to depression. Women are nearly twice as likely to suffer from depression as men, according to the National Center for Health Statistics (24).

This disparity is probably affected by hormonal and biological factors, considering that only women have premenstrual and postpartum depression. The same is true for antepartum (or perinatal depression) — which occurs during pregnancy. The American College of Obstetricians and Gynecologists estimates that perinatal depression affects one in seven women (25).

Women also have higher chances of developing seasonal affective depressive disorder, depressive symptoms in polar disorder, and persistent depressive disorder (26). It’s uncertain what causes such rates, but researchers speculate that environmental factors, such as peer pressure and different stressors that the modern world places on women, are the driving factor.

Others hypothesize that men and women have similar depression rates, but women are more willing to seek help than men.

So, how do both genders cope with depression?

Below, we explore some of the most common treatments.

How to Cope with Depression: Conventional Treatments

If you suspect that depression blocks you from living a normal life, talking about how you feel and discussing treatment options with qualified health professionals is the first step to successfully coping with depression.

There’s sound evidence that people with depression who go after treatment will finally find the much-desired relief in cognitive-behavioral therapy, medication, lifestyle changes, or a combination of all these three factors (27)

Lifestyle Modifications for Depression

Practicing mindfulness and exercising yoga can alleviate depression and stress that heightens it. You can also use journaling, arts, or alternative treatments like acupuncture or light therapy to cope with depression.

Diet modifications can reduce inflammation and help your brain absorb the nutrients it needs to maintain optimal functioning.

In a 2019 randomized controlled study, the authors found that self-reported symptoms of depression diminished significantly in just three weeks in young adults after they ditched highly processed carbohydrates in favor of a Mediterranean diet. In contrast, people who didn’t implement these modifications didn’t notice any changes in their depression scores (28).

Different Types of Psychotherapy in Coping with Depression

There are several types of psychotherapy for depression outlined by the Society of Clinical Psychology: (29)

Behavioral activation therapy

The goal of this treatment is to help you cope with depression by reversing its downward spiral by encouraging you to seek out activities that elevate your mood.

Cognitive-behavioral therapy (CBT)

CBT is aimed at changing the specific negative thought pattern so that you can develop a positive response to potentially stressful situations.

Interpersonal therapy

This is a very time-limited and structured treatment that tries to identify and improve problematic relationships and conditions directly linked to your depression.

Problem-solving therapy

It’s a subtype of CBT that teaches you how to be in charge of your life and cope with depression through managing your stressors, both big and small.

Self-control therapy

This is another behavioral therapy that trains you to become more resistant toA negative stressors and reduce your self-punishing thoughts and behaviors.

Conventional Antidepressants

Antidepressants are prescribed to alter the brain chemistry in a way that affects how neurons communicate with each other. The exact mechanism behind their mood-elevating properties is yet to be fully understood, but the fact is that these medications often work for some people (30, 31).

SSRIs (selective serotonin reuptake inhibitors

This class of drugs helps you cope with depression by targeting serotonin, a neurotransmitter that controls mood, sleep, and appetite. Popular SSRIs include Prozac, Celexa, and Zoloft.

SNRIs (serotonin norepinephrine reuptake inhibitors)

These medications block the reabsorption of serotonin and norepinephrine, which is other neurotransmitters responsible for mood control. Popular SNRIs include Cymbalta, Pristiq, and Effexor.

NDRIs (norepinephrine-dopamine reuptake inhibitors)

This group of drugs includes bupropion. They are designed to target dopamine receptors and make it more available for the body, therefore regulating our mood and emotions.

TCAs (tricyclic antidepressants)

TCAs include such medications as Pamelor and Tofranil. These medications are among the oldest antidepressants; these days, doctors rarely use them as the go-to treatment for depression. They’re mostly picked once the other classes of drugs have failed.

MAOIs)

Drugs like Nardil and Marplan were the first antidepressants invented. They’re rarely prescribed today due to their high-risk profile and severe negative interactions with certain foods and other medications.

Are Antidepressants Safe?

Antidepressants are generally considered safe if taken under a doctor’s supervision. The dose and the schedule should be circled in a way that relieves the symptoms without causing any negative reactions.

All antidepressants can have side effects, but some have a higher risk profile than others. Not all of them will be effective against your depression, so you may need to try several different medications, or a combination, prescribed by your doctor, before you can cope with depression.

Most antidepressants don’t act right away. It usually takes at least two weeks before you see results. For some people, the benefits of the drugs may not be experienced until they have taken them for as long as three months (32).

Abrupt cessation of your treatment may lead to a medical condition called antidepressant discontinuation syndrome (ADS). ADS is characterized by a wide range of responses, including flu, headaches, weight gain, stomach pain, nausea, and low mood (33).

It’s also worth noting that antidepressants aren’t addictive, unlike other substances that can be abused, such as alcohol, opioids, and barbiturates. People don’t have antidepressant cravings because they don’t get high from them, and they aren’t compulsively abused.

How to Cope with Treatment-Resistant Depression

If you’ve tried at least two types of antidepressants but to no avail, you may suffer from treatment-resistant depression (TRD). TRD is a serious illness that has been linked to suicidal ideation and suicide attempts.

Nearly one-third of patients with TRD attempt suicide in their lifetime, which is twice the rate of their treatment-responsive counterparts (35).

If you’re diagnosed with TRD, you may want to try some of the following alternative treatment options:

Esketamine

This nasal spray, sold under the name Spravato, has been approved by the FDA as a novel treatment for TRD (36). It contains ketamine, a veterinary anesthetic known as the street drug Special K. This medication must be administered in a medical office and shouldn’t be taken alongside oral antidepressants.

Electroconvulsive therapy (ECT)

ECT is the contemporary version of electroshock therapy. It involves a short electrical stimulation of the brain when the patient is sedated. The American Psychiatric Association (ECT) estimates that 80% of patients have recovered from severe, uncomplicated major depression after completing the treatments. However, ECT is also associated with a few side effects, such as short-term memory problems (37).

Transcranial magnetic stimulation (TMS)

This treatment uses rapidly changing magnetic fields to modulate the activity of specific brain regions. When conducted properly, it can immediately provide relief in patients with clinical depression (38).

Vagus nerve stimulation

This therapy involves connecting a device to the chest that treats it with regular mild electric pulses to the longest nerves that stem from the brain. A 2018 study published in the Journal of Clinical Psychiatry involving 600 patients with TRD concluded that vagus nerve stimulation significantly improved the symptoms of depression for many patients (39)

Psychedelic drugs

Although not approved by the FDA yet, microdosing psychedelic drugs such as MDMA or mushrooms produces a positive mood in chronically depressed people. These drugs have become the focus of a surge of research worldwide. The therapeutic potential of psychedelics appears promising and versatile. For example, a 2019 study released by the American Journal of Drug and Alcohol Abuse found that a synthetic analog of a psychedelic derived from the venom of certain toads provided positive results for depression and anxiety in humans (40).

10 Natural Antidepressants: Can They Help You Cope with Depression?

According to a research paper from 2017, up to 60% of people who take prescription drugs for depression experience an improvement in symptoms within several weeks, but the remaining 40% of people do not respond to such treatments (41).

This is where natural antidepressants may help. However, as with conventional antidepressants, the effects may vary between individuals and are not guaranteed to provide relief from severe depression in everyone.

1. SAM-e

Short for S-adenosylmethionine, SAM-e is a naturally occurring compound in the body. Several studies point to SAM-e as a natural antidepressant. However, research on its effects on people with depression is inconclusive. A 2011 analysis of the scientific literature found that SAM-e improved symptoms of depression in 8 studies. However, all these studies had methodological limitations (42). In another 2009 analysis, SAM-e produced better results than a placebo treatment in six placebo-controlled trials (43). However, SAM-e may not be safe for people with bipolar disorders because it can worsen manic periods.

2. St John’s Wort

St. John’s wort is sourced from a yellow flower that people have used in folk medicine for centuries. Some studies indicate that St. John’s wort can treat depression, but the results of these studies are inconclusive, and some of them have brought conflicting results. Researchers aren’t sure if St. John’s wort is an effective long-term treatment for depression. Some research suggests that St. John’s wort may change the way the brain processes dopamine, norepinephrine, and serotonin — in a similar way to conventional antidepressants (44). A 2011 review of previous studies found that St. John’s wort improved symptoms of depression in 10 studies (45).

3. Omega-3 Fatty Acids

Some types of high-fat fish, such as salmon or tuna, contain particularly high concentrations of omega-3 fatty acids, which are known for their anti-inflammatory properties. A 2019 analysis of 20 clinical trials concluded that large doses of omega-3 fatty acids may elevate mood and treat depression (46). Researchers don’t know what mechanism makes omega-3s effective. But as mentioned, their antidepressant effects are associated with the aforementioned anti-inflammatory qualities. That being said, you should avoid consuming omega-3s alongside blood thinners because they may also thin the blood (47).

4. Lavender

There’s a lot of anecdotal evidence surrounding the antidepressant and anti-anxiety effects of lavender. As it turns out, these effects are backed by science. In a 2012 systematic review of studies, inhaling lavender aromas helped people improve their sleep quality. However, the studies were done on small samples, and most had methodological issues, so there is a need for more in-depth research to support the initial findings (48). A 2015 randomized controlled trial provides more insight into using lavender as a natural antidepressant. The said study found that wearing a lavender aromatherapy patch can significantly improve the length and depth of sleep (49).

5. 5-HTP

5-hydroxytryptophan can alter serotonin levels in the brain in a similar way to some antidepressants. A few studies suggest that it can reduce the symptoms of depression (50). A 2016 study on mice suggested that it could be a potential remedy for treatment-resistant depression, although there’s not enough research on humans to confirm these findings (51). Some studies suggest that 5-HTP may impair the production of certain neurotransmitters, potentially worsening your mood over time — the longer you take it, the higher the risk of mood swings (52).

6. DHEA

5-Dehydroepiandrosterone is a steroid hormone produced by the adrenal glands. There’s limited evidence that points to DHEA as a natural antidepressant that may be effective in treating certain symptoms of health conditions, including PTSD, social anxiety, and depression. Unfortunately, DHEA can cause many side effects. It is known to interact with a range of medications, changing blood sugar levels, affecting fertility and menstruation, and increasing the risk of certain types of cancer.

7. CBD

CBD (cannabidiol) is the major non-intoxicating cannabinoid found in cannabis plants. Unlike THC, it won’t get you high, but it still offers a plethora of benefits for mental health. CBD is one of the safest natural antidepressants. The WHO reports that CBD is well-tolerated by humans even in doses as high as 1,500 mg daily taken for several weeks (53).

How Does CBD Work for Depression?

When you take CBD oil — the most popular form of CBD, which is an oily hemp extract — the CBD starts interacting with the endocannabinoid system (ECS), known as the master regulatory network.

The ECS is present in all systems and organs throughout the body; it promotes and helps maintain homeostasis between essential physiological and mental processes — including mood, memory, pain perception, appetite, sleep cycles, emotional processing, immune function, and more.

CBD has a similar structure to the body’s endocannabinoids. Although it doesn’t have an affinity with any of the cannabinoid receptors (CB1 and CB2), it does affect the way they process endocannabinoids, including anandamide (the bliss molecule).

CBD signals the ECS to produce more endocannabinoids while slowing their breakdown; as a result, these endocannabinoids can circulate in the body for longer, promoting calmness, a sense of balance, elevated mood, and better stress response (54).

On top of that, CBD can:

Inhibit the reuptake of serotonin

CBD uses a similar mechanism to SSRIs, but it doesn’t directly boost serotonin levels in the brain. Instead, it blocks the enzyme that breaks down serotonin so that the body can use it more efficiently (55).

Increase GABA levels in the brain

GABA is a natural inhibitory neurotransmitter that works as a hand brake for the brain. Optimal GABA levels help prevent neuroexcitation and thus keep anxiety and panic attacks at bay. Higher GABA levels are also associated with a calmer state of mind and improved focus (56).

Does CBD Interact with Conventional Antidepressants?

CBD is a potent inhibitor of Cytochrome P450, which is a system of enzymes that metabolize around 60% of pharmaceutical medications, including antidepressants (56).

It’s the same mechanism that’s used by grapefruit — hence a grapefruit warning on certain meds.

In short, CBD can compromise your liver’s ability to metabolize these drugs, resulting in too low or too high concentrations of the drug in your system (depending on the type of interaction). This may lead to either subtherapeutic effects or toxicity, both of which can be bad for your health.

Consulting a holistic doctor experienced in CBD and cannabis use will help you establish the right routine for your CBD oil supplementation and reduce the risk of potential interactions.

Related:

8. Ashwagandha

Ashwagandha is derived from Ginseng indica and is classified as an adaptogen. This means that the plant can help you deal with stress and improve your overall performance without compromising any of your physiological and psychological processes. It has been used for 3000 years in ancient medicine as a stress reliever and antidepressant. In one clinical placebo-controlled trial that involved 64 participants, 79% of those who took 600 mg of ashwagandha experienced a significant reduction in stress and depression. At the same time, the severity of both symptoms increased by 10% in the placebo group (57).

9. Medicinal Mushrooms

Medicinal mushrooms are a term that covers a group of mushrooms that offer a wide range of health benefits for the nervous system, immune system, and heart health. Research has found that medicinal mushrooms allow the user to reconnect with their emotions, unlike conventional antidepressants, which help the user cope with depression by dulling their emotions (58).

10. Vitamin B Complex

There’s strong evidence that a decrease in vitamin B-12 is associated with increased depression. Moreover, individuals with higher levels of vitamin B-12 are more likely to respond to their antidepressant treatment than people with low levels of this vitamin (59). If your blood tests indicate low vitamin B-12 levels, and you’ve recently found yourself depressed for an unknown reason, consider adding vitamin B complex to your supplementation plan.

Final Thoughts on How to Cope with Depression Using Natural Antidepressants

Contrary to a popular misconception, depression reaches far beyond regular sadness and baby blues. It’s a serious mental illness involving a wide range of symptoms, including both physiological and psychological reactions.

Diagnosing depression can be a hard nut to crack, as some individuals may hide it by showing some symptoms that can be interpreted as aggression, irritability, or a stubborn refusal to change their negative behavior.

Fortunately, as more resources are being invested into researching potential treatments for depression, people are receiving more tools to cope with this health condition before it takes over their lives and interferes with their daily functioning.

From psychotherapies to conventional medications and natural remedies — there’s a whole world of treatments that will help you cope with depression long-term rather than just masking the symptoms.

If you’re up for trying alternative depression treatments, we highly recommend CBD oil. CBD uses a multifaceted mechanism to combat the symptoms of depression as well as some of its underlying causes, such as endocannabinoid deficiencies.

Just make sure to consult your options with a doctor who is knowledgeable about using complementary treatments for depression. Doing so will help you figure out the right dosage and avoid potential cross-interactions with other medications.

13 CBD Facts & Common Misconceptions

With the peaking popularity of CBD as a potential therapeutic compound, there’s also a sea of misconceptions about this cannabinoid. You know how it is, people like to spread myths about different things and CBD is no exception. Read on to protect yourself against common misinformation.

The past year was a great milestone in the research on Cannabidiol. It doesn’t get you high, and yet, you can still experience a whole myriad of benefits that cannabis has to offer. Given this, we can fully understand the buzz among medical scientists and patients that CBD has created recently.

Numerous commercial companies and online retailers have hopped on the CBD bandwagon, claiming that hemp-derived CBD is the next big discovery, a versatile substance that can put an end to seizures, relieve chronic pain, reduce inflammation, and shrink tumor cells – without making users feel “stoned”.

However, the growing popularity of CBD has given rise to a whole litany of misconceptions about this cannabinoid. You already know that CBD is not a miracle cure, and you cannot use it as a quick fix to deal with literally any health issues.

But hey, some people really like to make stories up. Let’s debunk the top 13 misconceptions about CBD.

Top 13 CBD Myths & Misconceptions

Fasten your seatbelts and prepare yourself for a true myth ride.

Off we go!

1. CBD Is Medical, THC Is Recreational

How many times have you heard people saying that they are searching for “CBD, the medical compound, “not THC, the recreational one?” We cannot even count how many times our readers ask us about this on a daily basis.

As much as we admit that THC is still considered the recreational cannabinoid, due to the psychoactive high it produces, we cannot agree that it’s void of medical properties.

In fact, the long-stigmatized THC comes with amazing therapeutic qualities. According to scientists at the Scripps Research Center in San Diego, THC blocks an enzyme associated with the formation of 2-amyloid plaque, the main cause of Alzheimer ’s-related dementia [1].

Interestingly, the whole cannabis plant, which is a natural source of THC, continues to stay in the Schedule I drug classification. On the other hand, the same federal government that has demonized cannabis for such a long time seems to have nothing against recognizing single-molecule THC (used in Marinol, an anti-nausea drug) as a Schedule III pharmaceutical, a category reserved exclusively for substances with little abuse potential – it’s a bit hypocritical if you ask us.

2. THC Is the Bad Cannabinoid. CBD Is the Good Cannabinoid

This is an absolute winner on the list! Every drug fear-mongering looks like this: give credit to CBD and, at the same time, continue to stigmatize THC.

Some prohibition crusaders are sharing the good news about CBD to run even further with their holy insignia against high-THC cannabis, giving tetrahydrocannabinol as much of a bad reputation as they can.

Why is that?

We guess that it’s because CBD doesn’t make you feel high like THC does. We strongly stand against this reefer-madness classification between good and bad cannabinoids. Instead, we believe in whole-plant medicine, a concept popularized by Dr. Ethan Russo [2].

If you want to see the health benefits of cannabidiol in the big picture, we encourage you to embrace the power of the synergy achieved by all active compounds in the herb.

3. CBD Is Most Effective Without THC

Once again, we get back to Dr. Russo and the concept of the entourage effect. Numerous studies have shown that CBD and THC work best together. These two cannabinoids interact synergistically to boost the healing effects of one another.

British researchers have found that CBD strengthens THC’s anti-inflammatory properties in the animal model of colitis. Further, scientists from the California Pacific Medical Center in San Francisco discovered that a mix of CBD and THC produces a stronger anti-cancer effect than either compound; the study was conducted on brain and breast cancer cell families [3].

Complex clinical research has demonstrated that whole-plant extracts are more beneficial for neuropathic pain than isolated compounds.

4. Single-Molecule Pharmaceuticals Are Superior to ‘Crude’ Whole Plant Medicinals

Let’s break the federal government’s logic into bits and pieces. What Uncle Sam wants us to believe is that single-molecule drugs are more effective than whole-plant medicine. In other words, specific compounds of the marijuana plant (CBD, THC) have medicinal value, but the plant itself has no benefits at all, not to mention that it has a strong potential for abuse.

Wow, that sounds pretty bad, doesn’t it?

Let’s make it clear, the single-molecule favoritism reflects a cultural and political bias that benefits pharmaceutical corporations. It’s the legal way, FDA-approved way, but it is, by no means, the only way to benefit from cannabis – and definitely not the best way.

There are hundreds of active compounds in cannabis, including a whole palette of minor cannabinoids in addition to CBD and THC, aromatic terpenes, and various flavonoids. Each of these constituents comes with specific therapeutic qualities, but when consumed as a whole, they create what scientists and cannabis breeders refer to as the “ensemble effect” or the aforementioned “entourage effect.” [4].

The Food and Drug Administration, however, still labels plants as “food supplements.”

5. CBD Is Not Psychoactive

CBD oil in a bottle with hemp leaves on the side

While it’s true that CBD is not an intoxicant, it’s misleading to define CBD as a non-psychoactive compound. When a patient with clinical depression takes a low dose of a CBD-rich sublingual tincture and the compound makes them feel even slightly better for the first time in a long time, it’s a textbook example of mood alteration. By its definition, the word ‘psychoactive’ means ‘acting on the mind,’ and CBD fits into this definition like a glove.

That being said, it’s much better to say “CBD is not psychoactive like THC” or “CBD is not intoxicating, contrary to THC,” than to simply claim that it’s not psychoactive at all.

Don’t get us wrong, there is no chance that CBD will make you feel stoned. Instead, it can impact a person’s mind in many positive ways. Low-to-moderate doses of Cannabidiol are mildly stimulating. High doses of CBD, in turn, can serve as a decent sleep aid.

6. Psychoactivity Is Inherently An Adverse Side Effect

The whole machine behind the War on Drugs has made marijuana high an undesired side effect, and the federal government has used this common misconception as their main propaganda tool to discourage people from using the herb.

At the same time, pharmaceutical companies are allowed to synthesize medically active marijuana, it hasn’t been explained why mild euphoric sensations are basically wrong for a sick person or a healthy person.

It seems strange, to say the least, as in Greek, the word euphoria means “being in good health”, a state of complete well-being. The long-stigmatized euphoric features of cannabis are a far cry from being an undesired side effect. In fact, they are implicated in the medicinal value of the herb.

So, maybe it’s time to start thinking of cannabis as a medicine first, one that happens to have some psychoactive qualities (as if no medicine has ever had psychoactive effects), instead of perceiving it as an intoxicant that happens to have some medicinal benefits.

7. High Doses of CBD Work Better Than Low Doses

Yes, CBD isolates contain more CBD than whole plant CBD-rich extracts. But that doesn’t mean that isolated molecules are more effective. As a matter of fact, CBD isolates require higher doses to take effect than whole-plant products.

According to clinicians and patients, full-spectrum CBD extracts have a wider therapeutic window than isolates. A synergistic combination of THC, CBD, other cannabinoids, and terpenes can be effective at low doses – as little as 2.5mg THC and/or 2.5mg of CBD.

Some patients may require significantly higher amounts of those compounds to get the desired effects, but the increased influx of isolated CBD won’t solve the issue. Also, remember that both CBD and THC – and cannabis in general – have biphasic properties; in other words, low and high doses can induce the opposite effect. A high dose of CBD could be less effective than low-to-moderate doses when it comes to providing therapeutic effects.

8. CBD Converts to THC In a Person’s Stomach

CBD has been acknowledged as a safe substance that is well-tolerated in humans. However, people who are skeptical about cannabis, in general, are concerned about the potential side effects, which might impact CBD’s medical utility.

One of such misconceptions that leads to those concerns is the theory that CBD converts to the intoxicating THC in the stomach. Fortunately, there is sound evidence that this assumption is entirely wrong.

Extensive clinical trials have demonstrated that extremely high doses of CBD, like 600 mg of the cannabinoid, do not cause toxicity or THC-like psychoactive effects. In fact, it has turned out that CBD can neutralize the high from THC [5].

If you’re still not convinced whether we’re right or not, maybe the 2017 WHO report will make you change your mind:

As the WHO states:

“Stimulated gastric fluid does not exactly replicate physiological conditions in the stomach [and] spontaneous conversion of CBD to delta-9-THC has not been demonstrated in humans undergoing treatment.” [6]

9. Legalizing CBD, But Not Cannabis, Adequately Serves the Patient Population

Of all 50 states, 28 states have legalized medical marijuana (not just CBD) in various forms. Only nineteen U.S. states have enforced “CBD Only” laws. While we’re not going to deny that CBD has a huge therapeutic potential, some patients cannot fully benefit from CBD-rich remedies with little THC.

For example, parents of epileptic children have found that combining CBD extracts with THC or its raw, unheated version (THCA) is more effective for seizure control than CBD oil alone. Keep in mind that specific cannabis compounds are no one-fits-all solutions, and as such, some people need access to a broader spectrum of whole plant cannabis medicine, not just CBD-only remedies.

10. Marijuana Prohibition Doesn’t Apply to CBD. CBD Is Federally Legal If It Comes From the Seed Or Stalk of Hemp

CBD oil extract in bottle, a hemp bud and a gavel

Yet another big no-no! The only parts of the hemp plant from which CBD can be extracted are flower tops and leaves.

This misconception is commonly used by companies who want to look legitimate in the light of the contradictory U.S. laws, and if they claim that their oil is derived from hemp seed, they instantly lose credibility.

Even though Congress may soon vote to exclude hemp and CBD from the definition of “marihuana” under the Controlled Substances Act, cannabis still remains the law of the land according to the federal government.

We cannot interpret the Controlled Substances Act according to our outlook on the world. The current law, as unjust as it is, must be obeyed until the document is finally abolished.

11. CBD Is CBD – It Doesn’t Matter Where It Comes From

Actually, it doesn’t matter. While some low-resin industrial hemp crops may be a reasonable source of CBD, fiber hemp has a poor cannabinoid profile.

The largest concentration of CBD can be found in CBD-rich cannabis flower tops. Yes, specifically bred marijuana strains are currently the best source of Cannabidiol.

All products made from “entirely legal industrial hemp” require huge amounts of sourcing material to extract a small amount of CBD. This, in turn, can result in an increased risk of contaminants because hemp absorbs toxins from the soil.

On top of that, CBD extracted from industrial hemp or synthesized in a lab lacks essential therapeutic terpenes and other plant compounds that produce the synergy with CBD and THC to boost their healing properties.

Thankfully, as more research is being conducted on cannabinoids and their source, plant breeders are now aiming at satisfying the legal criteria for industrial hemp, which is less than 0.3% THC and more than 10% CBD by dry weight, while developing high-resin varieties from certain marijuana strains.

12. CBD Is Sedating

Cannabidiol can be sedative, but it doesn’t mean this quality shows up every time you consume CBD oil. It is best to know the different times of the day to take CBD by understanding the effects it can have in the morning and the evening.

Like we said, CBD has biphasic effects; simply put, when administered in low doses, earlier during the day, CBD can promote wakefulness and reduce daytime sleepiness. However, high doses of the cannabinoid before bedtime can have sedating effects, and as such, they can contribute to a good night’s sleep.

13. CBD Acts on the Cannabinoid Receptors

CBD has a long list of neurological effects, but they are not a result of Cannabidiol’s interaction with two cannabinoid receptors, CB1 and CB2.

While all other cannabinoids interact with CB1 and CB2 receptors, CBD has very little effect on either. Instead, CBD stimulates the endocannabinoid system to create more of its natural cannabinoids. It also slows their breakdown, thanks to which they can remain in your body for longer.

On top of that, CBD acts on over 60 molecular pathways, including the serotonin receptors, vanilloid receptors, orphan receptors, and nuclear receptors, which is why it can affect a person’s cognition, mood, appetite, pain perception, temperature control, immune responses, and cancer cells’ regression.

Don’t Spread Myths, Spread the Truth

As you can see, the list of common misconceptions about CBD is pretty long. Despite the increasing awareness of CBD as a therapeutic compound, the amount of misinformation on the Internet and in real life is disturbing, to say the least. Whether it’s caused by pure ignorance or intentional attempts at stigmatizing cannabis, we don’t know. Maybe it’s both. But we won’t stop the misconceptions from spreading until we start work at the grassroots. Now that you‘re familiar with the myths about CBD, don’t be afraid to publicly debunk them – even if you meet with negative reactions at first. Keep in mind that such reactions are most often caused by fear resulting from the lack of knowledge and years of being fed with propaganda against cannabis.

References:

  1. Currais et al. Amyloid Proteotoxicity Initiates An Inflammatory Response Blocked By Cannabinoids. NPJ Aging and Mechanism of Disease 2, Article number: 16012. Published in June 2016.
  2. Russo, Ethan B. “Taming THC: Potential Cannabis Synergy and Phytocannabinoid-Terpenoid Entourage Effects.” British Journal of Pharmacology 163.7 (2011): 1344–1364. PMC. Web. 17 Sept. 2018.
  3. McAllister SD, Christian RT, Horowitz MP, Garcia A, Desprez PY. Cannabidiol as a Novel Inhibitor of ld-1 Gene Expression in Aggressive Breast Cancer Cells. Molecular Cancer Therapeutics (2007):2921-7. Published in print, November 2007.
  4. Blasco-Benito S. et al. Appraising the “Entourage Effect”: Antitumor Action of a Pure Cannabinoid Versus a Botanical Drug Preparation In Preclinical Models of Breast Cancer. Biochemical Pharmacology (2018). pii: S0006-2952(18)30238-7. Published in June 2018.
  5. Bergamaschi MM, Costa Queiroz RG, Crippa JA, Zuardi AW. Safety And Side Effects of Cannabidiol, a Cannabis Sativa Constituent. Department of Toxicological and Food Sciences Analysis, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (2011), Current Drug Safety, 6, 000-000.
  6. World Health Organization. Cannabidiol (CBD): Critical Review Report. Expert Committee on Drug Dependence, Fortieth Meeting, June 2018.
Government shutdown continues as Trump directs Pentagon to use "all available funds" to pay troops

Government shutdown continues as Trump directs Pentagon to use “all available funds” to pay troops

What to know on Day 11 of the government shutdown:

  • Federal employees began receiving notices on Friday telling them they will be laid off in 60 days, CBS News has confirmed, after the Trump administration floated layoffs during the government shutdown. But some layoff notices issued to CDC employees were rescinded, multiple sources familiar with the situation told CBS News Saturday.  
  • More than 4,000 workers at seven federal agencies could get layoff notices, according to a court filing. 
  • House Speaker Mike Johnson said “we’re not in a good mood” as he noted Friday marks the first day that federal workers will not receive their full paychecks since the shutdown began on Oct. 1. The continued stalemate also makes it highly likely members of the military will miss their next paycheck, expected to arrive on Oct. 15.
  • There has been little movement in Congress toward ending the government shutdown in recent days. The Senate rejected motions to advance Democratic and Republican-backed spending bills for a seventh time Thursday and left town until Tuesday afternoon, meaning the deadlock will not be resolved until at least next week.
  • Several U.S. airports have experienced flight delays this week due to shortages of air traffic controllers, who are considered essential workers and have been working without pay since funding lapsed earlier this month. But they are expected to receive back pay once the shutdown ends. 
Police say an Indiana man's death

Police say an Indiana man’s death was no accident; His wife fights to prove she’s no murderer.

August 12, 2023, New Haven, Indiana. Shortly before morning broke in the home he rented with his wife Alison, at the base of a steep stairway, Kevin Davis‘ blood seeped onto the floor.

OFFICER GARRETT SHANEBROOK | New Haven Police Department (bodycam video): Where’s that blood coming from?

CORPORAL CADE HETRICK | New Haven Police Department: His face and his nose.

Det. James Krueger: The amount of blood was alarming. It was — it was everywhere.

Alison Davis had already given lead Detective James Krueger of the New Haven Police Department permission to search the house.

DET. JAMES KRUEGER (bodycam video):  If you do agree to that, I need you to sign there saying that you understand …

But she warned them about the bedroom, where their pit bull mix, Willow, would sometimes growl at strangers who approached.

ALISON DAVIS (bodycam video): She’s up in the bedroom, and she’s a guard dog.

DET. JAMES KRUEGER: OK.

ALISON DAVIS: And I don’t know if she’d do anything, and I don’t want anything to happen to her.

DET. JAMES KRUEGER: Right now, what I won’t do is, I won’t go in that room.

ALISON DAVIS: OK.

AN ACCIDENTAL FALL?

Kevin had been rushed to Parkview Regional Medical Center in critical condition. After speaking with first responders and breaking the tragic news to her loved ones, Alison also headed to Parkview.

Peter Van Sant: So you go to the hospital?

Steve Krause: Yes.

Steve Krause watched his daughter try to will Kevin back to consciousness.

Steve Krause: Their favorite phrase for one another was “babe.” … And Alison’s up there, “Hey, babe, you’re gonna be OK. Hey, babe, you know, I’m here with you. Hey, babe, I love you.”

Kasey Klemm: She had blood on her fingernails, cuticles, and on her phone. I could tell that she had been crying, but she kind of just looked like in shock.

Alison’s best friendis Kasey Klemm.

Kasey Klemm: They had her in like a little waiting room with a chaplain. And I was trying to calm her down to ask questions, you know, like what was going on?

Back at the house, Krueger lifted restrictions and cleared the bloody scene. It was horrific. But at this point, he believed it was an accident.

Det. James Krueger: Well, maybe he took a head plant down the stairs. I don’t know. I wasn’t there.

Kasey Klemm: The detective said … I think we’re done here.

Alison stayed at the hospital. But back home, all that blood needed to be cleaned up.

Kasey Klemm: You don’t think about that right? … Like, who cleans it up?

Steve Krause: I said well, I will go do it.

Peter Van Sant: You had permission to do this?

Steve Krause: Correct.

Peter Van Sant: Permission from the lead detective in this case?

Steve Krause: Correct.

Peter Van Sant: How upsetting was this process of cleaning?

Steve Krause: Well, it’s very upsetting. … sometimes I’d get — become overwhelmed and need to gather myself, um, to finish, um, what I’d come to do.

Including tending to Willow, who had been left upstairs in their bedroom with the door closed.

Steve Krause: Alison was concerned that this dog hadn’t been left out … They had no children, so the dog was … like a child.

Throughout that frantic morning, Alison and her family quietly prayed.

Steve Krause: I’m praying can we just, you know, wake up, you know, wake up. You look like you’re sleeping, just wake up.

Kevin and Alison were a part of a tight group of friends who were regulars at the East Haven Tavern where Jodi Espy and Jessica Eakright take care of the crowd.

Jessica Eakright: Our customers become our family around here.

The news that Kevin was in critical condition hit hard.

Jodi Espy: Everybody was just talking like, “Oh my gosh, he was just here. That’s so sad.”

Kevin and Alison had been at the Tavern just hours earlier.

Jessica Eakright: It was hard not to be a friend of Alison’s because she just made everybody feel like you mattered.

Kevin, a skilled landscaper, had a big personality that matched his big heart.

Todd Spessert: Kevin Davis was, uh, just a nice guy … always hard working … ready to help anybody out at any time.

Close friends Todd Spessert and Jason Young scrambled to see Kevin.

Jason Young: We all met at the hospital.

Todd Spessert: Yeah. Jason Young: We talked to Alison and her parents.

Jason Young: … definitely, she had been crying, but she was holding back.

Todd Spessert: She was —  she was a mess.

Peter Van Sant: She was devastated?

Jason Young and Todd Spessert: Yes.

The scene was overwhelming.

Todd Spessert: Yeah, he … he’s uh brain dead, there’s nothing left in there.

Peter Van Sant:  God, just a few hours earlier, he was sitting right over here, right?

Todd Spessert: Correct.

Peter Van Sant: Do you say anything to Kevin?

Jason Young: Oh yeah, yup. … I told him it’s like … I feel really bad about this. And it shouldn’t have happened, and I wish you were still here. 

Peter Van Sant: And did you have a chance to say goodbye to your friend?

Jason Young: Yeah. I said goodbye there. Yep.

Todd Spessert: They were — yeah, then they were talking about, you know, donating his organs and stuff. And I was like — I was like, wow.

Peter Van Sant: He was an organ donor?

Kasey Klemm: Yes, yes. She was very proud of him for that, too.

His life support would be disconnected. Soon, 40-year-old Kevin Davis was gone. At 33, Alison was a widow.

Kasey Klemm: They were just a happy type of couple that would dance in the kitchen to music together, just the two of them. Like that’s just who they were. They were great together.

It shook their friend Deontae Bristol.

Deontae Bristol: I was just holding back tears because we were just hanging out. Like I was just hanging out with this guy.

Jessica Eakright: It’s devastating. Not just because he’s no longer here, but because the circumstances surrounding it are traumatic. READ MORE…